Where Little Frogs Come From

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A fascinating time lapse video by wildlife filmmaker Francis Chee of cell division in a developing frog egg, as it splits from two cells into several million over the course of 33 hours. Chee sez:

… it was done with a custom designed microscope based on the “infinity optical design” It is not available by any manufacturer. I built it. I used LEDs and relevant optics to light the egg. They too were custom designed by me. The whole microscope sits on anti-vibration table. I have to say that it doesn’t matter too much what microscope people use to perform this. There are countless other variables involved in performing this tricky shot, such as for example: the ambient temperature during shooting; the time at which the eggs were collected; the handling skills of the operator; the type of water used; lenses; quality of camera etc etc.

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